Searchable abstracts of presentations at key conferences in endocrinology

ea0033p65 | (1) | BSPED2013

Modulation of mesenchymal stem cell differentiation by alterations in GH action and cell–matrix interaction

Wang Ruijun Jessie , Yarwood Stephen , Dalby Matthew , Ahmed Faisal

Introduction: Mesenchymal stem cells (MSCs) are a type of multipotent cells readily found within the bone marrow, capable of undergoing self-renewal and giving rise to cells with different characteristics, such as, osteoblasts, adipocytes and chondrocytes. MSC differentiation requires optimal cell–matrix interaction and is also dependent on a number of growth factors.Aim: To investigate the effect of GH, Rho-associated kinase (ROCK) and extracellula...